A new study in mice suggests that ibuprofen, perhaps the most common pain relief medication, could affect aspects of liver health.
Ibuprofen is a common nonsteroidal anti-inflammatory drug (NSAID). In the United States, drugstores tend to sell the brand-name versions Motrin or Advil.
In the U.S. and other countries, ibuprofen is readily available over the counter. People tend to use it to relieve pain or the symptoms of a mild cold.
Like any other drug, ibuprofen can have side effects. One of them is liver damage, though this is rare.
And now, a new study in mice — from researchers at the University of California, Davis — suggests that ibuprofen’s adverse effect on liver health may be more significant than doctors suspect.
“The liver plays a key role in energy metabolism and is essential for whole-body homeostasis [the stabilization of bodily functions] via the regulation of glucose, lipid, and amino acid metabolism,” the researchers explain in their study paper, which appears in Scientific Reports.