- Five factors are associated with sepsis development in patients with cellulitis, according to a prospective study.
Why this matters
- Given the serious and potentially deadly risks associated with sepsis, identification of risk factors is needed.
- 10.7% of patients developed sepsis.
- In multivariate analysis, the following 5 factors were associated (ORs) with sepsis development:
- Leukocyte count: 1.080 per 1000 cells/μL (P=.003).
- Serum creatinine: 2.238 per mg/dL (P=.001).
- Drawing of blood cultures: 2.984 (P=.003).
- Modification of initial antimicrobial regimen: 2.154 (P=.03).
- Maximum length of cellulitis: 1.029 per cm (P=.004).
- 606 patients hospitalized with cellulitis were analyzed for development of sepsis and associated factors.
- Funding: Infectious Diseases Working Group of the Spanish Society of Internal Medicine.
- Observational study design.
- Heterogenous treatments used.